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Hotels in Santee, SC

Set along Interstate 95, Santee is located in central South Carolina in Orangeburg County. Found in the Santee River Valley, Santee is set on the shores of Lake Marion. Outdoor enthusiasts may explore the 2,500-acre Santee State Park – ideal for hiking, birding, canoeing and kayaking.

Santee visitors may also shop through Santee Village Outlet Mall, or tee off at the Santee National Golf Course, Lake Marion Golf Course, and the Santee Cooper Country Club. There are many ways to enjoy a stay in Santee – visit soon and discover your new favorite area attraction.

Best Western Plus Santee Inn

I-95 Exit 98, Santee SC 29142
Phone: +1 803-854-3089  |  Fax: (803) 854-3093  |  Hotel Details  |  Reservations

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